With the number of drug overdose deaths dropping, some are celebrating. But is there a risk in declaring victory too early and cutting funding for prevention? Today’s guest on Grieving Out Loud, an addiction researcher at Stanford, says not so fast. About 72,000 overdose deaths a year still exceeds the total number of Americans who died in the Vietnam War.
In this episode of Grieving Out Loud, Dr. Kepner shares what history has taught us about past drug epidemics, and how those lessons can guide the path forward while preventing as many deaths as possible.
This is a major moment in the fight against counterfeit pills. “Sophie” Xaiofei Chen has been sentenced to 4 years and 4 months for trafficking pill-making equipment into the U.S., one of the few times a supplier with no direct drug trafficking charges has faced serious consequences.
Learn how this case signals a broader federal crackdown on companies supplying the tools used to manufacture deadly fake pills, why this matters, what’s next in 2026, and how this prosecution fits into America’s struggle with fentanyl-laced counterfeit medications.
The Financial Crimes Enforcement Network, a Bureau of the United States Department of the Treasury, has published a document outlining out Chinese Money Laundering works.
The U.S. Food and Drug Administration (FDA) announced that states and tribes proposing importation programs can use “a static baseline approach for the cost-savings analysis” instead of trying to account for changes in unpredictable markets.
The latest available data, compiled in January of this year, shows fatal overdoses over the previous 12-month periodincreased by roughly 1,400 deaths.
“This slight increase reflects historic data and suggests that the U.S. saw more overdose deaths in January 2025 than it did in January 2024,” the CDC said in a statement sent to NPR. “We are working on analyses to better understand geographic trends.”
The CDC data suggests roughly 82,138 deaths during the 12-month period ending in January 2025. That would be a significant increase from the December 2024 report, but it’s still far below the overdose crisis peak of 114,664 recorded in August 2023.
Still, after seventeen months of declines in fatal overdoses that stunned drug policy experts and an unprecedented 27 percent drop in drug deaths in 2024, some addiction researchers described this report as troubling.
Keith Humphreys, a researcher at Stanford University, said the new CDC data could be an early warning that drug death declines brought on by a number of factors, including the end of COVID pandemic disruptions and weaker fentanyl being sold on U.S. streets, could be fading.
“If we assume it’s not a blip, this makes it more likely that the sudden drop [in fatal overdoses] was a one-off event rather than a fundamental change in epidemic dynamics,” Humphreys said in an email.
Most overdose deaths in the U.S. are caused by fentanyl, but researchers who sample the street drug supply have warned of an increasingly dangerous mix of chemicals being sold by dealers, including cocaine and methamphetamines, as well veterinary tranquilizers such as medetomidine and xylazine.
“Overdose trends are not a one-way street, and there will be periodic local increases,” said Nabarun Dasgupta, who studies overdose trends at the University of North Carolina.
His analysis of the latest CDC data suggested “most of the country is still trending down in the right direction.”
According to Dasgupta, the “increase in predicted national numbers are driven primarily by upticks in Texas, Arizona, California and Washington.”
